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Zendesk Collaborates with Microsoft

CIO Insider Team | Thursday, 20 November, 2025
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Zendesk, a pioneer in AI-powered service, has deepened its long-standing collaboration with Microsoft to bring Zendesk’s service directly into Microsoft’s AI ecosystem through two new integrations: Microsoft Agent 365, and Zendesk Agent for Microsoft 365 Copilot. These integrations deliver seamless, secure, and intelligent service experiences within the Microsoft 365 tools employees use every day.

● Microsoft Agent 365: Zendesk is a launch partner for Microsoft Agent 365, a secure and autonomous platform that manages Zendesk AI agents within Microsoft’s environment. Using Microsoft security and compliance tools, Agent 365 acts as a control plane autonomously managing Zendesk tickets, accessing knowledge bases, and maintaining seamless communication for Microsoft 365 users and support teams.

● Zendesk Agent for Microsoft 365 Copilot: This integration brings AI-powered Zendesk support inside Microsoft 365 apps, allowing employees to submit support tickets, check statuses, add notes, and escalate issues all without leaving their workflow.

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We're combining the power of Microsoft 365 Copilot's intelligence with Zendesk's modern service platform, enabling employees to resolve IT, HR, and Finance issues seamlessly within the tools they use every day

Craig Flower, Zendesk Chief Information Officer says, "Our collaboration with Microsoft on Agent 365 and Zendesk Agent for Microsoft 365 Copilot is a pivotal moment for Zendesk. This collaboration not only solidifies our position as a leader in enterprise AI automation but also ensures that Zendesk remains at the forefront of the evolving digital worker landscape. By integrating with Agent 365 and Microsoft 365 Copilot, we are empowering our customers with both autonomous and streamlined support capabilities, optimising operations, and ultimately delivering a more efficient and reliable employee experience within Microsoft 365."

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Srini Raghavan, Corporate Vice President, Microsoft Copilot and Agent Ecosystem at Microsoft says, "AI is transforming how organizations deliver employee service, and Microsoft’s collaboration with Zendesk is leading that change by enabling a new era of intelligent support. We're combining the power of Microsoft 365 Copilot's intelligence with Zendesk's modern service platform, enabling employees to resolve IT, HR, and Finance issues seamlessly within the tools they use every day.”



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